Description

Adenylyl(2'>5')Uridine Ammonium is a high-purity, chemically defined nucleotide derivative of significant interest in biochemical research and development. This compound serves as a critical building block and research tool for studying RNA structure, function, and enzymatic processes. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in nucleic acid chemistry, antiviral research, and molecular biology.

Application

• Biochemical Research: As a substrate or intermediate for studying RNA ligases, nucleotidyltransferases, and other enzymes involved in RNA metabolism and editing.
• Antiviral Drug Discovery: Investigation of nucleotide analogs targeting viral replication mechanisms, particularly for RNA viruses.
• Nucleic Acid Chemistry: Serving as a specialized monomer or precursor for the chemical synthesis of oligonucleotides with unique 2'-5' linkage motifs.
• Enzymology Studies: Used in assays to understand the specificity and kinetics of enzymes that recognize or modify adenosine and uridine nucleotides.
• Diagnostic Probe Development: Potential use in the design of labeled probes for detecting specific RNA sequences or enzymatic activities.
• Reference Standard: Employed as an analytical standard in quality control and method development for nucleotide-based pharmaceuticals or reagents.

Basic Information

Product Name	Adenylyl(2'>5')Uridine Ammonium
CAS No.	102029-66-3
Molecular Formula	C19H25N7O13P2 • xNH3
Molecular Weight	645.40 g/mol (free acid, anhydrous)
Synonyms	2'-5' Adenylyluridine Ammonium Salt; p5'A2'p5'U Ammonium Salt; Adenosine(2'-5')uridine Ammonium; Ap2'p5'U ammonium; 2',5'-Oligoadenylate Derivative; A2'p5'U; 2-5A Core (A2'p5'U) Ammonium Salt; 5'-O-Phosphonoadenylyl-(2'→5')-uridine Ammonium
EINECS	Contact for details

Quality Control

Our Adenylyl(2'>5')Uridine Ammonium is manufactured under controlled conditions to ensure high chemical purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label. This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (UV)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Ammonium Content	Contact for details
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.