Description

5-Iodouridine 5'-Monophosphate Sodium Salt is a modified nucleotide monophosphate of significant interest in biochemical research and pharmaceutical development. This compound serves as a critical building block and precursor for the synthesis of oligonucleotides and probes used in molecular diagnostics and genetic studies. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in nucleoside chemistry and antiviral drug discovery.

Application

• Biochemical Research: Acts as a substrate or intermediate in enzymatic studies and metabolic pathway investigations.
• Oligonucleotide Synthesis: Used as a modified monomer for incorporating iodine-labeled uridine into DNA or RNA strands for structural and functional studies.
• Antiviral Agent Development: Investigated as a potential precursor or analog in the research of nucleoside-based antiviral therapeutics.
• Diagnostic Probe Manufacturing: Employed in the creation of labeled probes for hybridization assays and other molecular diagnostic techniques.
• Enzyme Inhibition Studies: Useful for studying enzyme mechanisms that involve nucleotide binding or processing.
• Radiopharmaceutical Precursor: Can serve as a precursor for iodine-125 or iodine-131 labeled compounds used in research and imaging.

Basic Information

Product Name	5-Iodouridine 5'-Monophosphate Sodium Salt
CAS No.	103404-82-6
Molecular Formula	C9H10IN2NaO9P
Molecular Weight	479.05 g/mol
Synonyms	5-Iodo-UMP sodium salt; 5-Iodouridine 5'-phosphate sodium salt; 5-Iodo-uridine 5'-monophosphate sodium salt; Sodium 5-iodouridine 5'-monophosphate; 5-Iodouridylic acid sodium salt; Uridine, 5-iodo-, 5'-(dihydrogen phosphate), sodium salt (1:1); 5-Iodo-2'-deoxyuridine 5'-monophosphate sodium salt (common misnomer, verify structure)
EINECS	Contact for details

Quality Control

Our 5-Iodouridine 5'-Monophosphate Sodium Salt is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.