Description

Adenylosuccinic Acid Sodium Salt is a key biochemical intermediate in the purine nucleotide biosynthetic pathway. This compound is essential for research and development in enzymology and metabolic studies, particularly concerning the enzyme adenylosuccinate lyase. It serves as a critical substrate or standard for laboratories and manufacturers focused on nucleotide chemistry, diagnostic assay development, and pharmaceutical research targeting metabolic disorders.

Application

• Biochemical Research: Used as a substrate for studying the activity and kinetics of adenylosuccinate lyase (ADSL) in purine biosynthesis.
• Diagnostic Reagent Manufacturing: Serves as a key component in the formulation of enzymatic assay kits for diagnosing inborn errors of metabolism, such as adenylosuccinate lyase deficiency.
• Pharmaceutical Reference Standard: Employed as a high-purity analytical standard for quality control in the production of nucleotide-related APIs and fine chemicals.
• Enzyme Inhibition Studies: Utilized in screening and development of potential inhibitors for therapeutic applications in cancer and immunological research.
• Metabolic Pathway Analysis: Acts as a crucial intermediate in in vitro reconstructions of the purine salvage and de novo synthesis pathways for metabolic profiling.

Basic Information

Product Name	Adenylosuccinic Acid Sodium Salt
CAS No.	102129-67-9
Molecular Formula	C14H15N5O11PNa2 • xH2O
Molecular Weight	Anhydrous: 531.24 g/mol
Synonyms	Adenylosuccinate Sodium Salt; Sodium Adenylosuccinate; 6-[(1S)-1,2-Dicarboxyethyl]amino-9H-purin-9-yl]-5-O-phosphono-β-D-ribofuranose Sodium Salt; 5'-Phosphorylribosyl-4-(N-succinoamino)-5-aminoimidazole Sodium Salt; ADSL Substrate; 5-Amino-4-imidazole-N-succinocarboxamide ribotide Sodium Salt; IMP-Aspartate Ligase Product; SAICAR Sodium Salt (Note: SAICAR is a related but distinct intermediate).
EINECS	Contact for details

Quality Control

Our Adenylosuccinic Acid Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent tests for moisture and endotoxin levels where applicable. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom synthesis and purification to meet specific pharmacopeial or internal standards are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption. For extended storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	6.0 - 8.0
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.