Description

(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[[2-phenyl-2-[[(2E)-2-[(4-propoxybenzoyl)hydrazinylidene]acetyl]amino]acetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid is a high-purity, semi-synthetic chemical intermediate derived from the 6-aminopenicillanic acid (6-APA) core. This compound matters as a critical building block in the research and development of novel β-lactam antibiotics and other advanced pharmaceutical agents. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and antibiotic resistance studies.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel penicillin and cephalosporin derivatives for antibiotic research.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to develop new antimicrobial agents.
• Bioconjugation Studies: Employed in the development of targeted drug delivery systems and antibody-drug conjugates (ADCs) due to its reactive functional groups.
• Enzyme Inhibition Studies: Serves as a potential inhibitor or probe in biochemical assays targeting bacterial cell wall synthesis enzymes.
• Fine Chemical Synthesis: A specialized intermediate for custom synthesis services catering to the pharmaceutical and biotechnology industries.
• Academic Research: Used in university and institutional labs for advanced studies in organic synthesis and pharmacology.

Basic Information

Product Name	(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[[2-phenyl-2-[[(2E)-2-[(4-propoxybenzoyl)hydrazinylidene]acetyl]amino]acetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
CAS No.	143729-84-4
Molecular Formula	C30H33N5O7S
Molecular Weight	607.68 g/mol
Synonyms	6-[[(2E)-2-[(4-Propoxybenzoyl)hydrazinylidene]acetyl]amino]penicillanic acid derivative; 6-APA hydrazone derivative; Penicillin G hydrazone analog; (2E)-N'-(4-Propoxybenzoyl)-2-[2-(phenylglycylamino)acetamido]penicillanic hydrazide; 143729-84-4; 6-[(Phenylglycyl)amino]penicillanic acid (4-propoxybenzoyl)hydrazone
EINECS	Contact for details

Quality Control

Our (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[[2-phenyl-2-[[(2E)-2-[(4-propoxybenzoyl)hydrazinylidene]acetyl]amino]acetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.