Description

Ristomycin A aglycone, 5,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(1-oxododecyl)amino]-β-D-glucopyranuronosyl]-42-O-α-D-mannopyranosyl-N15-methyl- is a complex, semi-synthetic glycopeptide derivative of the natural antibiotic ristomycin. This compound is of significant interest for its role as a key intermediate in the research and development of novel antimicrobial agents, particularly against resistant Gram-positive bacteria. It serves as a critical building block for pharmaceutical chemists and researchers in antibiotic discovery, structure-activity relationship (SAR) studies, and medicinal chemistry programs aimed at overcoming bacterial resistance.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of next-generation glycopeptide antibiotics and novel antimicrobial conjugates.
• Medicinal Chemistry Research: Used in Structure-Activity Relationship (SAR) studies to understand and enhance the antibacterial efficacy and pharmacokinetic properties of ristomycin derivatives.
• Antibiotic Discovery: Serves as a scaffold for developing new agents targeting vancomycin-resistant enterococci (VRE) and methicillin-resistant *Staphylococcus aureus* (MRSA).
• Biochemical Research: Employed as a tool compound to study the mechanism of action of glycopeptide antibiotics, particularly their binding to bacterial cell wall precursors.
• Reference Standard: Used as a high-purity analytical standard in quality control and method development for related pharmaceutical products.

Basic Information

Product Name	Ristomycin A aglycone, 5,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(1-oxododecyl)amino]-β-D-glucopyranuronosyl]-42-O-α-D-mannopyranosyl-N15-methyl-
CAS No.	110882-85-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	5,31-Dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(1-oxododecyl)amino]-β-D-glucopyranuronosyl]-42-O-α-D-mannopyranosyl-N15-methylristomycin A aglycone; Ristomycin A aglycone derivative; Chlorinated Ristomycin A aglycone conjugate; Dodecanoylated Ristomycin A aglycone; Ristomycin intermediate; Glycopeptide antibiotic intermediate; Antibacterial research compound.
EINECS	Contact for details

Quality Control

Our Ristomycin A aglycone derivative is produced under controlled conditions to ensure high chemical purity and batch-to-batch consistency, suitable for demanding research applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.