Description

Ethyl 3-Fluoro-4-Phenylbenzoylformate is a high-purity, specialized organic intermediate featuring a benzoylformate ester core with strategically positioned fluorine and phenyl substituents. This molecular architecture makes it a valuable synthon for constructing complex molecules in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working in medicinal chemistry and fine chemical synthesis. The compound's specific reactivity profile enables its use in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of novel herbicides and fungicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Chemistry: Employed in the research and development of advanced organic materials, including liquid crystals and organic semiconductors.
• Chemical Biology Probes: Useful for synthesizing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring fluorinated aromatic compounds.

Basic Information

Product Name	Ethyl 3-Fluoro-4-Phenylbenzoylformate
CAS No.	951888-52-1
Molecular Formula	C16H13FO3
Molecular Weight	272.27 g/mol
Synonyms	Ethyl 3-Fluoro-4-phenylbenzoylformate; Ethyl 2-oxo-2-(3-fluoro-4-phenylphenyl)acetate; 2-(3-Fluoro-4-biphenylyl)-2-oxoacetic Acid Ethyl Ester; 3-Fluoro-4-phenylbenzoylformic Acid Ethyl Ester; Ethyl (3-Fluoro-4-phenylbenzoyl)formate; Ethyl α-oxo-3-fluoro-4-phenylbenzeneacetate; 951888-52-1; NSC 781106
EINECS	Contact for details

Quality Control

Every batch of Ethyl 3-Fluoro-4-Phenylbenzoylformate is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with relevant industry standards for research-grade and GMP-starting materials. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles as measured by advanced techniques like HPLC, GC, NMR, and IR spectroscopy.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.