Description

Methyl 5-Bromo-4-Chloro-2-Fluorobenzoate is a high-purity, multi-halogenated benzoate ester serving as a critical building block in advanced organic synthesis. Its precise halogen substitution pattern makes it an indispensable intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the halogenated aromatic core contributes to bioactivity and environmental stability.
• Liquid Crystal Material (LCM) Development: Serves as a fluorinated building block for creating high-performance liquid crystal molecules used in display technologies.
• Organic Electronic Materials: Intermediate in the synthesis of fluorinated organic semiconductors and charge-transport materials for OLEDs and other electronic devices.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and material science research, enabling structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules under cGMP conditions where applicable.

Basic Information

Product Name	Methyl 5-Bromo-4-Chloro-2-Fluorobenzoate
CAS No.	951884-02-9
Molecular Formula	C8H5BrClFO2
Molecular Weight	267.48 g/mol
Synonyms	5-Bromo-4-chloro-2-fluorobenzoic acid methyl ester; Methyl 5-bromo-4-chloro-2-fluorobenzoate; Benzoic acid, 5-bromo-4-chloro-2-fluoro-, methyl ester; 2-Fluoro-5-bromo-4-chlorobenzoic acid methyl ester; Methyl 2-fluoro-5-bromo-4-chlorobenzoate
EINECS	Contact for details

Quality Control

Every batch of Methyl 5-Bromo-4-Chloro-2-Fluorobenzoate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profile by HPLC/GC is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.