Description

3-((1R,3R,5S)-8-Azabicyclo[3.2.1]Octan-3-Yl)Benzamide Hydrochloride is a high-purity, chiral pharmaceutical intermediate and research chemical. This compound is of significant value for the development of novel active pharmaceutical ingredients (APIs) targeting the central nervous system and other therapeutic areas. It is primarily required by pharmaceutical R&D laboratories, process development chemists, and fine chemical manufacturers engaged in the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of potential drug candidates, particularly those with tropane or related bicyclic amine scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs for new therapeutic agents.
• Process Chemistry Development: Serves as a critical starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Reference Standard: Employed as an analytical standard for quality control and method validation in API manufacturing.
• Biochemical Tool Compound: Utilized in pharmacological assays to study receptor interactions and biological pathways.

Basic Information

Product Name	3-((1R,3R,5S)-8-Azabicyclo[3.2.1]Octan-3-Yl)Benzamide Hydrochloride
CAS No.	949904-53-4
Molecular Formula	C15H21N3O • HCl
Molecular Weight	295.81 g/mol
Synonyms	(1R,3R,5S)-3-(3-Carbamoylphenyl)-8-azabicyclo[3.2.1]octane hydrochloride; 3-(8-Azabicyclo[3.2.1]oct-3-yl)benzamide hydrochloride (isomer unspecified); 949904-53-4; 3-(Endo-8-azabicyclo[3.2.1]oct-3-yl)benzamide HCl; Benzamide, 3-((1R,3R,5S)-8-azabicyclo[3.2.1]oct-3-yl)-, hydrochloride
EINECS	Contact for details

Quality Control

Our 3-((1R,3R,5S)-8-Azabicyclo[3.2.1]Octan-3-Yl)Benzamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with stringent specifications for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.