Description

Benserazide Hydrochloride is a high-purity pharmaceutical intermediate and active ingredient of critical importance in the treatment of Parkinson's disease. Its primary commercial value lies in its role as a peripheral aromatic L-amino acid decarboxylase (AADC) inhibitor, which enhances the efficacy of co-administered levodopa. This compound is essential for manufacturers in the pharmaceutical and fine chemical sectors developing advanced neurological therapeutics.

Application

• Active Pharmaceutical Ingredient (API) in combination therapies for Parkinson's disease.
• Pharmaceutical Intermediate for the synthesis of finished dosage forms (e.g., tablets, capsules).
• Research & Development chemical in neurological and biochemical studies.
• Reference Standard for quality control and analytical method development in pharmaceutical laboratories.
• Key component in the production of levodopa/benserazide combination drugs.
• Starting material for further chemical synthesis and derivative preparation.

Basic Information

Product Name	Benserazide Hydrochloride
CAS No.	14046-64-1
Molecular Formula	C10H15N3O5 • HCl
Molecular Weight	293.71 g/mol
Synonyms	Benserazide HCl; DL-Serine 2-(2,3,4-trihydroxybenzyl)hydrazide hydrochloride; Ro 4-4602/1; (2S)-2-Amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide hydrochloride; L-Seryl-2-(2,3,4-trihydroxybenzyl)hydrazide hydrochloride; Serazide Hydrochloride
EINECS	Contact for details

Quality Control

Our Benserazide Hydrochloride is manufactured under strict quality management systems. The product undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every batch upon request, supporting compliance with cGMP and relevant pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤1.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.