Description

R-(+)-Lisuride Hydrogen Maleate is a high-purity, enantiomerically pure derivative of the ergot alkaloid lisuride. This compound serves as a critical pharmaceutical reference standard and active pharmaceutical ingredient (API) intermediate for research and development. It is essential for organizations engaged in neurological and endocrine research, as well as for manufacturers developing advanced therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control in API manufacturing.
• Active Pharmaceutical Ingredient (API) Intermediate: A key chiral building block in the synthesis of dopaminergic and serotonergic agents.
• Neurological Research: Critical for in-vitro and in-vivo studies targeting dopamine and serotonin receptors.
• Endocrine Research: Utilized in studies investigating prolactin secretion and related disorders.
• Process Development & Scale-up: Serves as a benchmark material for optimizing synthetic routes in process chemistry.
• Regulatory Submissions: Provides essential characterization data for drug master files (DMFs) and regulatory dossiers.

Basic Information

Product Name	R-(+)-Lisuride Hydrogen Maleate
CAS No.	19875-60-6
Molecular Formula	C₂₀H₂₆N₄O • C₄H₄O₄
Molecular Weight	454.49 g/mol
Synonyms	Lisuride Maleate; (R)-Lisuride Hydrogen Maleate; (+)-Lisuride Maleate; N'-[(8α)-9,10-Didehydro-6-methylergolin-8-yl]-N,N-diethylurea (Z)-butenedioate; Lisenil; Dopergin; Lysenyl; Revanil; Eunal
EINECS	Contact for details

Quality Control

Our R-(+)-Lisuride Hydrogen Maleate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and compliance with relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% (R-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.