Description

Epi-Galanthamine CAS NO 1668-85-5 is a stereoisomer of the natural alkaloid galanthamine, serving as a key intermediate and reference standard in advanced pharmaceutical research and development. This compound is of significant interest for its role in studying acetylcholinesterase inhibition and exploring novel therapeutic pathways. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in neuroscience, drug discovery, and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: Critical building block in the synthetic pathways for developing galanthamine-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and tool compound in neuroscience studies targeting acetylcholinesterase and nicotinic receptors.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for quality control and method validation in analytical laboratories.
• Drug Discovery & Development: Employed in structure-activity relationship (SAR) studies to develop new cognitive enhancers and neuroprotective agents.
• Fine Chemical Synthesis: A valuable chiral precursor for the asymmetric synthesis of complex natural products and specialized organic molecules.

Basic Information

Product Name	Epi-Galanthamine
CAS No.	1668-85-5
Molecular Formula	C₁₇H₂₁NO₃
Molecular Weight	287.35 g/mol
Synonyms	(-)-Epi-Galanthamine; (3aS,4S,6aS,11bS)-3a,4,5,6,6a,11b-Hexahydro-9-hydroxy-4,6a-methano[1,3]benzodioxolo[4,5-g]quinolin-10(3H)-one; Galanthamine Epimer; 4-Epi-Galanthamine; Narwedine Epimer; Lycoramine Isomer
EINECS	Contact for details

Quality Control

Our Epi-Galanthamine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development purposes. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a detailed Certificate of Analysis (COA). We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.