Description

Levodopa CAS NO 59-92-7 is the levorotatory isomer of L-3,4-dihydroxyphenylalanine (L-DOPA), a direct metabolic precursor to the neurotransmitter dopamine. This compound is of critical importance in the pharmaceutical industry for its therapeutic efficacy in managing neurological disorders. It is primarily required by manufacturers of active pharmaceutical ingredients (APIs) for the production of medications targeting Parkinson's disease and related conditions.

Application

• Pharmaceutical API: The primary and most significant application is as the active pharmaceutical ingredient in medications for the treatment of Parkinson's disease, often formulated with a decarboxylase inhibitor (e.g., Carbidopa).
• Neurological Research: Used as a critical biochemical reagent in neuroscience and pharmacological research to study dopaminergic pathways, neurotransmission, and related disease models.
• Reference Standard: Serves as a high-purity analytical reference standard in quality control laboratories for the identification and assay of pharmaceutical products.
• Intermediate Synthesis: Acts as a key chiral building block or intermediate in the synthesis of more complex pharmaceutical compounds and prodrugs.

Basic Information

Product Name	Levodopa
CAS No.	59-92-7
Molecular Formula	C9H11NO4
Molecular Weight	197.19 g/mol
Synonyms	L-DOPA; L-3,4-Dihydroxyphenylalanine; (-)-DOPA; Levodopum; Dopar; Larodopa; 3-Hydroxy-L-tyrosine; (S)-2-Amino-3-(3,4-dihydroxyphenyl)propanoic acid
EINECS	200-445-2

Quality Control

Our Levodopa is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical use. We offer grades compliant with major pharmacopoeias, including USP and EP monographs. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, available upon request to ensure full traceability and regulatory compliance for our B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Specific Rotation	-12.0° to -14.0° (c=1 in 1N HCl)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.