Description

Romergoline is a high-purity pharmaceutical intermediate and research chemical with significant importance in the development of therapeutic agents. Its value lies in its role as a key building block for synthesizing advanced compounds targeting neurological pathways. This product is essential for research institutions, pharmaceutical R&D laboratories, and manufacturers developing treatments for central nervous system disorders.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of dopaminergic and serotonergic receptor-targeting drugs.
• Neurological Research: Used in biochemical and pharmacological studies to investigate receptor binding and signal transduction mechanisms.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and validation in quality control laboratories.
• Active Pharmaceutical Ingredient (API) Development: Employed in the research and scale-up phases for novel therapeutic compounds.
• Academic & Contract Research: Utilized in university and CRO settings for exploratory studies in neurochemistry and medicinal chemistry.

Basic Information

Product Name	Romergoline
CAS No.	107052-56-2
Molecular Formula	C₁₆H₁₈N₄O
Molecular Weight	282.34 g/mol
Synonyms	Romergoline; 6-Methyl-8β-[(methylthio)methyl]ergoline; 8β-[(Methylthio)methyl]-6-methylergoline; Cabergoline Impurity; Cabergoline Related Compound A; FCE 21336; (8β)-6-Methyl-8-[(methylthio)methyl]ergoline
EINECS	Contact for details

Quality Control

Our Romergoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substances, residual solvent analysis, and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We support development and commercial projects requiring standards aligned with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.