Description

3-o-Methyl-6-Fluoro-L-Dopa (OMFD) is a fluorinated derivative of L-DOPA, serving as a crucial intermediate in the synthesis of advanced radiopharmaceuticals and positron emission tomography (PET) tracers. Its primary value lies in enabling the development of diagnostic agents for neurological research, particularly in studying the dopaminergic system. This high-purity compound is essential for pharmaceutical R&D laboratories, radiochemistry facilities, and academic institutions focused on neuroimaging and neurodegenerative disease research.

Application

• Radiopharmaceutical Precursor: Key intermediate for the synthesis of Fluorine-18 labeled PET tracers, such as [18F]FDOPA.
• Neurological Research: Used in the development of diagnostic agents for studying Parkinson's disease, brain tumors, and other disorders of the dopaminergic system.
• PET Tracer Development: Critical building block in the research and production of novel positron emission tomography imaging agents.
• Biochemical Research: Serves as a reference standard and a tool compound in studies of amino acid metabolism and neurotransmitter synthesis.
• Pharmaceutical Intermediate: Employed in the synthetic pathways for developing new therapeutic agents targeting the central nervous system.

Basic Information

Product Name	3-o-Methyl-6-Fluoro-L-Dopa (OMFD)
CAS No.	114077-01-9
Molecular Formula	C10H12FNO4
Molecular Weight	229.21 g/mol
Synonyms	OMFD; 6-Fluoro-3-O-methyl-L-DOPA; (2S)-2-Amino-3-(2-fluoro-4,5-dihydroxyphenyl)-2-methylpropanoic acid; 3-OMe-6-F-DOPA; L-3-O-Methyl-6-fluorodopa; 6-Fluoro-O-methyl-L-Dopa; Fluoromethyl-DOPA; 3-O-Methyl-6-fluoro-L-3,4-dihydroxyphenylalanine
EINECS	Contact for details

Quality Control

Our 3-o-Methyl-6-Fluoro-L-Dopa is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and chiral purity, NMR, and mass spectrometry for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical and diagnostic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.