Description

Pimavanserin CAS NO 107456-06-4 is a selective serotonin inverse agonist and antagonist, primarily targeting the 5-HT2A receptor. This compound is of significant commercial and research interest as the active pharmaceutical ingredient (API) in medications for treating Parkinson's disease psychosis. It is essential for pharmaceutical manufacturers, research institutions, and developers of central nervous system (CNS) therapeutics. Our supply ensures high purity and consistency for critical formulation and development work.

Application

• Active Pharmaceutical Ingredient (API) for the manufacture of antipsychotic medications.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Key intermediate in advanced research and development of novel CNS-targeting therapeutics.
• Pharmacological studies investigating serotonin receptor modulation and related pathways.
• Process development and scale-up activities for generic drug manufacturing.
• Academic and institutional research in neuropharmacology and neurodegenerative diseases.

Basic Information

Product Name	Pimavanserin
CAS No.	107456-06-4
Molecular Formula	C25H34FN3O2
Molecular Weight	427.56 g/mol
Synonyms	ACP-103; 1-(4-Fluorobenzyl)-3-(4-(2-methylpropoxy)benzyl)urea; N-(4-Fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropoxy)phenyl)methylurea; Pimavanserin Tartrate (salt form); Pimavanserin Hemitartrate; NUPLAZID (brand name API)
EINECS	Contact for details

Quality Control

Our Pimavanserin is produced and tested under strict quality management systems. Each batch undergoes comprehensive analysis to ensure it meets high-purity standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and can be tailored to meet specific pharmacopeial requirements (e.g., USP, EP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5%
Single Unknown Impurity	≤0.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.