Description

Pramipexole 2Hcl CAS NO 104617-85-8 is the dihydrochloride salt form of Pramipexole, a potent and selective dopamine D2/D3 receptor agonist. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy and safety of finished pharmaceutical formulations. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of treatments for neurological disorders.

Application

• Pharmaceutical API: Primary active ingredient in the manufacture of prescription medications for Parkinson's disease and Restless Legs Syndrome (RLS).
• Neurological Research: Used as a reference standard and investigational compound in preclinical and clinical studies targeting dopaminergic pathways.
• Generic Drug Production: Essential for formulating bioequivalent generic versions of branded pramipexole medications.
• Dosage Form Development: Incorporated into various solid oral dosage forms such as tablets and capsules.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for quality control and analytical method validation in laboratories.

Basic Information

Product Name	Pramipexole 2Hcl
CAS No.	104617-85-8
Molecular Formula	C10H17N3S • 2HCl
Molecular Weight	302.25 g/mol
Synonyms	Pramipexole Dihydrochloride; (S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole Dihydrochloride; SND 919; Mirapexin (salt form); Mirapex (salt form); Pramipexole HCl; Pramiracetam Impurity
EINECS	Contact for details

Quality Control

Our Pramipexole 2Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to meet stringent pharmaceutical-grade specifications, including identity, purity, and impurity profile. Certificates of Analysis (COA) detailing results against relevant pharmacopeial standards (e.g., USP, EP) are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive (store away from light); ensure containers are kept sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Optical Rotation	Specific range provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.