Description

7-Methoxy-2,1,3-Benzoxadiazole-4-Sulfonyl Chloride (Saltdata: Free) is a specialized sulfonyl chloride derivative of a benzoxadiazole heterocycle, serving as a critical building block for the synthesis of advanced fluorescent probes and labeling reagents. Its core value lies in its high reactivity, enabling the selective derivatization of amines and other nucleophiles to create sensitive detection systems for analytical chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic industries who require high-purity intermediates for developing assays and sensor technologies.

Application

• Fluorescent Probe Synthesis: A key precursor for creating sulfonamide-based fluorescent tags and sensors used in bioimaging and cellular analysis.
• HPLC Derivatization Reagent: Used to label and enhance the detection sensitivity of amines, amino acids, and peptides in liquid chromatography applications.
• Bioconjugation Chemistry: Enables the covalent attachment of fluorophores or other reporter molecules to proteins, antibodies, and oligonucleotides.
• Chemical Biology Research: Employed in the development of activity-based probes (ABPs) for studying enzyme function and metabolic pathways.
• Diagnostic Kit Manufacturing: Serves as an intermediate in the production of reagents for clinical diagnostics and immunoassays.
• Material Science: Can be utilized to functionalize surfaces or polymers with fluorescent properties for sensor applications.

Basic Information

Product Name	7-Methoxy-2,1,3-Benzoxadiazole-4-Sulfonyl Chloride (Saltdata: Free)
CAS No.	944780-94-3
Molecular Formula	C7H5ClN2O4S
Molecular Weight	248.64 g/mol
Synonyms	7-Methoxy-2,1,3-benzoxadiazole-4-sulfonyl chloride; 4-(Chlorosulfonyl)-7-methoxy-2,1,3-benzoxadiazole; 7-Methoxy-4-sulfonylchloride-2,1,3-benzoxadiazole; MBD-SO2Cl; 7-Methoxybenzofurazan-4-sulfonyl chloride; 4-Chlorosulfonyl-7-methoxy-2,1,3-benzoxadiazole; 7-Methoxy-2,1,3-benzoxadiazole-4-sulfonochloride; 7-MeO-BD-Sulfonyl Chloride
EINECS	Contact for details

Quality Control

Our 7-Methoxy-2,1,3-Benzoxadiazole-4-Sulfonyl Chloride is manufactured under strict quality protocols to ensure batch-to-batch consistency and high chemical purity suitable for sensitive research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity, identity, and impurity profiles. Our quality systems are designed to meet the rigorous standards expected in pharmaceutical and analytical reagent supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain optimal stability and reactivity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.