Description

N,N'-Didansyl-L-Cystine is a high-purity, dansyl-labeled derivative of the amino acid cystine, widely recognized by its CAS number 18468-46-7. This compound serves as a critical fluorescent probe and analytical standard in advanced biochemical research and pharmaceutical development. It is essential for scientists and quality control professionals in the fields of proteomics, fluorescence spectroscopy, and method validation for amino acid analysis.

Application

• Fluorescent Labeling Agent: Used as a sensitive derivatization reagent for the HPLC and LC-MS analysis of thiol-containing compounds like cysteine and glutathione.
• Biochemical Research Standard: Acts as a certified reference material (CRM) for calibrating instruments and validating analytical methods in proteomics and metabolomics studies.
• Pharmaceutical Intermediate: Employed in the research and development of novel drug candidates and diagnostic agents that target sulfur-based metabolic pathways.
• Protein & Peptide Chemistry: Utilized in studies of disulfide bond formation, protein folding, and structure-function relationships due to its specific fluorescence properties.
• Quality Control & Assurance: Serves as a system suitability standard in pharmaceutical QC labs to ensure the accuracy of chromatographic assays for amino acids.

Basic Information

Product Name	N,N'-Didansyl-L-Cystine
CAS No.	18468-46-7
Molecular Formula	C26H28N4O6S2
Molecular Weight	556.66 g/mol
Synonyms	L-Cystine, N,N'-didansyl-; Didansylcystine; N,N'-Bis(5-dimethylaminonaphthalene-1-sulfonyl)-L-cystine; Dansyl-L-cystine; DNS-Cystine; 5-(Dimethylamino)naphthalene-1-sulfonyl cystine derivative; Fluorescent cystine derivative
EINECS	Contact for details

Quality Control

Our N,N'-Didansyl-L-Cystine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements of research and analytical applications. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.