Description

o-Phthalaldehyde (CAS NO 643-79-8) is a high-purity aromatic dialdehyde that serves as a critical derivatization agent and versatile building block in advanced chemical synthesis. Its primary commercial value lies in its exceptional reactivity as a fluorogenic reagent for the sensitive detection and quantification of primary amines and amino acids. This compound is essential for industries requiring precise analytical methods and high-quality fine chemical intermediates, particularly in pharmaceutical quality control, biotechnological research, and the production of specialty polymers and agrochemicals.

Application

• HPLC Derivatization Reagent: Widely used as a pre-column or post-column derivatizing agent for the fluorometric detection of primary amines, amino acids, and peptides in high-performance liquid chromatography (HPLC).
• Biochemical Staining & Diagnostics: Employed as a rapid and sensitive fluorogenic stain for proteins and for visualizing neuronal tissue in histology, as well as in diagnostic kits.
• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of various active pharmaceutical ingredients (APIs), heterocyclic compounds, and complex organic molecules.
• Crosslinking Agent: Utilized in polymer chemistry and material science for the crosslinking of proteins, polymers, and resins to modify their physical properties.
• Disinfectant & Sterilant Formulation: An effective active ingredient in high-level disinfectant solutions for medical and dental instruments, valued for its efficacy against a broad spectrum of microorganisms.
• Research & Development: A valuable reagent in organic synthesis laboratories for constructing complex molecular architectures via condensation and cyclization reactions.

Basic Information

Product Name	o-Phthalaldehyde
CAS No.	643-79-8
Molecular Formula	C8H6O2
Molecular Weight	134.13 g/mol
Synonyms	OPA; Phthaldialdehyde; 1,2-Benzenedicarboxaldehyde; Benzene-1,2-dicarboxaldehyde; o-Phthalic dicarboxaldehyde; Phthalic Dialdehyde; o-Diformylbenzene; 1,2-Phthalaldehyde
EINECS	211-402-2

Quality Control

Our o-Phthalaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for analytical and synthetic applications. Each lot undergoes comprehensive testing, including assay, identification, and impurity profile analysis via advanced techniques like HPLC. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We can supply material compliant with various in-house specifications and support customer-specific quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent absorption of atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents, strong bases, and amines.

Specification

Item	Specification
Appearance	Pale yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	55 - 58 °C
Loss on Drying	≤ 1.0 %
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.