Description

9-Anthryldiazomethane is a highly reactive and specialized derivatization reagent, primarily used as a fluorescent labeling agent for carboxylic acids. Its core value lies in its ability to form stable, intensely fluorescent esters, enabling the sensitive detection and quantification of target analytes via HPLC or LC-MS. This compound is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and analytical chemistry sectors who require high-sensitivity methods for complex sample analysis.

Application

• HPLC Fluorescent Derivatization: Pre-column labeling of carboxylic acids, including fatty acids, bile acids, and prostaglandins, for enhanced detection sensitivity.
• LC-MS Analysis: Used as a derivatizing agent to improve the ionization efficiency and detection of carboxylic acid-containing metabolites in metabolomics and bioanalytical studies.
• Pharmaceutical Impurity Profiling: Detection and quantification of trace carboxylic acid impurities in active pharmaceutical ingredients (APIs) and drug products.
• Biomarker Research: Fluorescent tagging of carboxylated biomarkers in biological fluids (e.g., serum, urine) for disease research and diagnostic assay development.
• Food and Environmental Analysis: Sensitive determination of carboxylic acid contaminants or additives.
• Organic Synthesis Intermediate: Serves as a reagent for the introduction of the anthryl group into target molecules in specialized synthetic pathways.

Basic Information

Product Name	9-Anthryldiazomethane
CAS No.	10401-59-9
Molecular Formula	C₁₅H₁₀N₂
Molecular Weight	218.26 g/mol
Synonyms	9-ADAM; 9-Anthryldiazomethane; 9-(Diazomethyl)anthracene; Anthracene-9-diazomethane; 9-Anthryldiazomethane reagent; ADAM reagent; 9-Diazoanthracene
EINECS	Contact for details

Quality Control

Our 9-Anthryldiazomethane is produced and handled under strict quality-controlled conditions to ensure batch-to-batch consistency and optimal reactivity. Each lot undergoes comprehensive analysis, including purity assay and functional performance testing. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (typically >97% by HPLC), and related substances is supplied with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) to minimize decomposition and oxidation. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Solubility	Soluble in common organic solvents (e.g., DMF, DMSO, dichloromethane)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.