Description

Dipyrenylcystine n-Hydroxysulfosuccinimidyl Monoester is a specialized heterobifunctional crosslinking reagent designed for advanced bioconjugation. This compound is critical for researchers and developers requiring precise, stable linkages between biomolecules, such as proteins and peptides, and various probes or surfaces. It is primarily utilized in the life sciences sector for applications in assay development, diagnostic kit manufacturing, and advanced materials science, where controlled and efficient conjugation is paramount.

Application

• Bioconjugation Reagent: For creating stable amide bonds between primary amines and carboxyl groups in proteins, peptides, and other biomolecules.
• Fluorescent Probe Attachment: Enables the site-specific labeling of biomolecules with pyrenyl-based fluorophores for fluorescence spectroscopy and imaging studies.
• Immunoassay Development: Used in the synthesis of enzyme-antibody or hapten-protein conjugates for ELISA and other diagnostic platforms.
• Surface Functionalization: Facilitates the covalent immobilization of biomolecules onto sensor chips, microarrays, and nanoparticles for biosensing and diagnostic devices.
• Drug Delivery System Research: Aids in the development of targeted drug conjugates by linking therapeutic agents to targeting ligands.
• Biomaterial Modification: Employed to modify hydrogels and polymer scaffolds with bioactive peptides to enhance cell-material interactions.

Basic Information

Product Name	Dipyrenylcystine n-Hydroxysulfosuccinimidyl Monoester
CAS No.	100839-37-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-(3-(2,5-Dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-N-(2-(1-pyrenyl)ethyl)-L-cystinyl-N-(1-pyrenylmethyl)amide; NHS-Pyrene Crosslinker; Pyrenyl-NHS Ester; Heterobifunctional Pyrene Crosslinker; 1-Pyrenebutanoic acid, succinimidyl ester derivative; N-Hydroxysulfosuccinimide ester of dipyrenylcystine
EINECS	Contact for details

Quality Control

Our Dipyrenylcystine n-Hydroxysulfosuccinimidyl Monoester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive research and development applications. Certificates of Analysis (COA) detailing lot-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at temperatures between -20°C to -10°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Solubility	Soluble in DMF, DMSO; slightly soluble in acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.