Description

n-(2,4-Dinitrophenyl)-L-Valine Methyl Ester is a specialized chiral amino acid derivative, serving as a critical intermediate in advanced organic synthesis. Its value lies in the precise structural features of the dinitrophenyl protecting group and the L-valine ester moiety, which are essential for constructing complex, biologically active molecules. This compound is primarily needed by research institutions and pharmaceutical development teams focused on peptide chemistry, proteomics, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Proteomics Research: Used in the development of reagents and probes for studying protein structure, function, and interactions.
• Chiral Synthesis: Employed as a chiral auxiliary or precursor in asymmetric synthesis to induce stereoselectivity.
• Bioconjugation Chemistry: Utilized for labeling or modifying biomolecules due to the reactivity of the dinitrophenyl group.
• Chemical Biology: Serves as a tool compound for enzyme inhibition studies and mechanism-based probe design.
• Academic & Industrial R&D: Fundamental research material for novel synthetic methodologies and compound library development.

Basic Information

Product Name	n-(2,4-Dinitrophenyl)-L-Valine Methyl Ester
CAS No.	10420-77-6
Molecular Formula	C₁₄H₁₇N₃O₆
Molecular Weight	323.30 g/mol
Synonyms	L-Valine, N-(2,4-dinitrophenyl)-, methyl ester; Methyl N-(2,4-dinitrophenyl)-L-valinate; DNP-L-Valine methyl ester; DNP-Val-OMe; N-2,4-DNP-L-valine methyl ester; (S)-Methyl 2-((2,4-dinitrophenyl)amino)-3-methylbutanoate; 2,4-Dinitrophenyl-L-valine methyl ester; Valine, N-(2,4-dinitrophenyl)-, methyl ester, L-
EINECS	Contact for details

Quality Control

Our n-(2,4-Dinitrophenyl)-L-Valine Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.