Description

Methyl 2-Bromo-4-Chloro-6-Fluorobenzoate is a high-purity, multi-halogenated benzoate ester serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the halogen pattern for enhanced bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized aromatic compounds for organic electronic materials and liquid crystals.
• Custom Synthesis and Contract Manufacturing: A vital reagent for fine chemical companies offering bespoke synthesis services to the life sciences industry.
• Academic and R&D Laboratories: Used in methodological studies and exploring new synthetic pathways involving halogenated aromatics.

Basic Information

Product Name	Methyl 2-Bromo-4-Chloro-6-Fluorobenzoate
CAS No.	943975-33-5
Molecular Formula	C8H5BrClFO2
Molecular Weight	267.48 g/mol
Synonyms	2-Bromo-4-chloro-6-fluorobenzoic acid methyl ester; Methyl 2-bromo-4-chloro-6-fluorobenzoate; Benzoic acid, 2-bromo-4-chloro-6-fluoro-, methyl ester; Methyl 2-bromo-4-chloro-6-fluorobenzoate; Methyl α-bromo-γ-chloro-ε-fluorobenzoate
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Bromo-4-Chloro-6-Fluorobenzoate is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis. Specifications are aligned with industry standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed due to potential moisture sensitivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC Area %)	≥99.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.