Description

Methyl 2-Amino-5-Chloro-4-Fluorobenzoate CAS NO 936540-27-1 is a high-purity fluorinated benzoate ester derivative, serving as a critical advanced pharmaceutical intermediate (API) and versatile building block in organic synthesis. Its value lies in its multifunctional molecular structure, which enables precise chemical modifications for creating complex, biologically active molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic compounds used in electronic display materials and organic light-emitting diodes (OLEDs).
• Organic Synthesis Building Block: The reactive amino, chloro, and fluoro substituents make it a versatile synthon for palladium-catalyzed cross-coupling reactions, nucleophilic substitutions, and ester transformations.
• Dye & Pigment Intermediate: Employed in the development of specialized fluorinated dyes and pigments with unique color fastness and spectral properties.

Basic Information

Product Name	Methyl 2-Amino-5-Chloro-4-Fluorobenzoate
CAS No.	936540-27-1
Molecular Formula	C8H7ClFNO2
Molecular Weight	203.60 g/mol
Synonyms	2-Amino-5-chloro-4-fluorobenzoic acid methyl ester; Methyl 5-chloro-4-fluoro-2-aminobenzoate; Benzoic acid, 2-amino-5-chloro-4-fluoro-, methyl ester; 5-Chloro-4-fluoro-2-aminobenzoic acid methyl ester; 936540-27-1; Methyl 2-amino-5-chloro-4-fluorobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-5-Chloro-4-Fluorobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light as indicated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.