Description

2-Fluoro-4-(3-Trifluoromethylphenyl)Benzoic Acid is a high-value fluorinated aromatic carboxylic acid building block. This compound is critical for its role in the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its unique trifluoromethyl and fluorine substituents impart desirable biological activity and metabolic stability. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and pesticides, leveraging the fluorine and trifluoromethyl groups for enhanced efficacy.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Electronic Materials: Employed in the synthesis of monomers and polymers for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A versatile reagent for exploring new chemical reactions and creating compound libraries in medicinal chemistry.
• Advanced Polymer Modification: Used to introduce fluorinated aromatic groups into polymer backbones to alter thermal and chemical resistance properties.

Basic Information

Product Name	2-Fluoro-4-(3-Trifluoromethylphenyl)Benzoic Acid
CAS No.	926222-59-5
Molecular Formula	C14H8F4O2
Molecular Weight	284.21 g/mol
Synonyms	2-Fluoro-4-[3-(trifluoromethyl)phenyl]benzoic acid; 4'-Fluoro-3'-(trifluoromethyl)[1,1'-biphenyl]-4-carboxylic acid; [1,1'-Biphenyl]-4-carboxylic acid, 4'-fluoro-3'-(trifluoromethyl)-; 2-Fluoro-4-(3-trifluoromethylphenyl)benzoic acid; 2-Fluoro-4-(α,α,α-trifluoro-m-tolyl)benzoic Acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(3-Trifluoromethylphenyl)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.