Description

α-Galcer Analog 8 is a synthetic glycolipid analog designed for advanced immunological research and development. This compound serves as a potent and specific activator of invariant Natural Killer T (iNKT) cells, a critical component of the immune system's bridge between innate and adaptive immunity. It is an essential tool for researchers and developers in the fields of immunotherapy, vaccine adjuvants, and pharmaceutical discovery, particularly for targeting cancer, infectious diseases, and autoimmune disorders.

Application

• Immunological Research: As a key reagent for studying iNKT cell biology, activation pathways, and cytokine production.
• Vaccine Adjuvant Development: Used to enhance the efficacy of vaccines by potently stimulating cellular immune responses.
• Cancer Immunotherapy: Investigated for its potential to activate iNKT cells to target and eliminate tumor cells.
• Infectious Disease Models: Employed in preclinical studies to understand and modulate immune defense against pathogens.
• Autoimmune Disease Research: Utilized to explore the role of iNKT cells in regulating immune tolerance and inflammation.
• Pharmaceutical Screening: Serves as a reference standard or active component in high-throughput screening assays for novel immunomodulators.

Basic Information

Product Name	α-Galcer Analog 8
CAS No.	922727-14-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	α-Galactosylceramide Analog 8; KRN7000 Analog; C-Glycoside Analog of α-GalCer; iNKT Cell Agonist 8; Synthetic Glycolipid Agonist; α-GalCer Mimetic; Immunostimulatory Glycolipid
EINECS	Contact for details

Quality Control

Our α-Galcer Analog 8 is produced under stringent quality management systems to ensure batch-to-batch consistency and reliability for critical research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to high-purity standards suitable for pharmaceutical research and biological testing.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and easily oxidized; therefore, containers should be sealed under nitrogen or argon after each use and allowed to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.