Description

n-Acetylglucosamine-n-Acetylmuramyl-Alanyl-Isoglutaminyl-Alanyl-Glycerol Dipalmitoyl is a synthetic peptidoglycan fragment, specifically a muramyl dipeptide (MDP) derivative conjugated with a dipalmitoyl glycerol moiety. This compound is of significant interest for its role as a potent immunomodulator and adjuvant, mimicking the minimal bioactive structure of bacterial cell walls. It is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors for advanced vaccine development, immunology studies, and novel therapeutic agent formulation.

Application

• Vaccine Adjuvant Research: As a synthetic MDP derivative, it serves as a key component in the development of novel vaccine formulations to enhance immune response.
• Immunology & Immunostimulant Studies: Used in laboratory research to study innate immune system activation, particularly through NOD2 receptor pathways.
• Pharmaceutical Development: A critical intermediate or active ingredient in the synthesis of advanced immunotherapeutic agents and drug delivery systems.
• Biochemical Research: Employed as a standard or probe in studies related to peptidoglycan recognition, macrophage activation, and inflammatory signaling.
• Liposome & Nanoparticle Conjugation: The dipalmitoyl tail facilitates incorporation into lipid-based delivery platforms for targeted immunomodulation.

Basic Information

Product Name	n-Acetylglucosamine-n-Acetylmuramyl-Alanyl-Isoglutaminyl-Alanyl-Glycerol Dipalmitoyl
CAS No.	130114-83-9
Molecular Formula	C84H147N9O26
Molecular Weight	1687.1 g/mol
Synonyms	MDP-Glycerol Dipalmitate; Muramyl Dipeptide Glycerol Dipalmitoyl; N-Acetylmuramyl-L-alanyl-D-isoglutaminyl-L-alanyl-glycerol dipalmitate; L-Ala-γ-D-Glu-mDAP(NH2)-D-Ala-Gly-; GMDP Dipalmitoyl; Adjuvant Peptide Derivative; Immunostimulant MDP Analog; NAG-NAM-L-Ala-D-iGln-L-Ala-Gly-DP
EINECS	Contact for details

Quality Control

Our n-Acetylglucosamine-n-Acetylmuramyl-Alanyl-Isoglutaminyl-Alanyl-Glycerol Dipalmitoyl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and NMR for structural verification, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity (Cell-based assay)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.