Description

2-Deoxy-2-(3-Hydroxytetradecanamido)-3-o-(3-Hydroxytetradecanyl)Glucopyranosyl Dihydrogen Phosphate is a complex synthetic glycolipid derivative, structurally related to key bacterial cell wall components. This compound is of significant interest for its role as a critical intermediate in advanced biochemical research and pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical companies engaged in immunology, vaccine development, and the synthesis of novel therapeutic agents.

Application

• Immunological Research: As a synthetic analog of bacterial lipid A or related structures for studying innate immune responses and Toll-like receptor (TLR) signaling pathways.
• Vaccine Adjuvant Development: Serves as a key intermediate or model compound in the research and synthesis of next-generation vaccine adjuvants to enhance immune response.
• Pharmaceutical Synthesis: An important building block for the chemical synthesis of complex glycoconjugates and potential novel anti-infective or immunomodulatory agents.
• Biochemical Tool Compound: Used in enzymatic studies, particularly those involving kinases, phosphatases, or glycosyltransferases that act on similar lipid-linked sugar substrates.
• Lipidomics and Metabolomics: Acts as a reference standard or an internal standard in mass spectrometry-based analysis of complex lipid species.
• Cell Biology Studies: Employed in research exploring membrane biophysics, lipid raft formation, and the role of specific glycolipids in cellular recognition processes.

Basic Information

Item	Detail
Product Name	2-Deoxy-2-(3-Hydroxytetradecanamido)-3-o-(3-Hydroxytetradecanyl)Glucopyranosyl Dihydrogen Phosphate
CAS No.	132760-25-9
Molecular Formula	C40H78NO13P
Molecular Weight	812.02 g/mol
Synonyms	3-O-(3-Hydroxytetradecyl)-2-deoxy-2-[(3R)-3-hydroxytetradecanamido]-α-D-glucopyranosyl dihydrogen phosphate; Lipid X analog; Synthetic glycolipid phosphate; 2-Deoxy-2-(3R-hydroxytetradecanoylamino)-3-O-(3R-hydroxytetradecyl)-α-D-glucopyranosyl phosphate; Glucosamine-based lipid A precursor; D-Glucopyranose derivative, 2-deoxy-2-[(3R)-3-hydroxytetradecanamido]-3-O-[(3R)-3-hydroxytetradecyl]-, 1-(dihydrogen phosphate); Monophosphoryl lipid A intermediate
EINECS	Contact for details

Quality Control

Our 2-Deoxy-2-(3-Hydroxytetradecanamido)-3-o-(3-Hydroxytetradecanyl)Glucopyranosyl Dihydrogen Phosphate is produced under strict quality management protocols suitable for research and development. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided, reporting results from NMR, HPLC, and mass spectrometry. We support custom synthesis and purification to meet specific research-grade or higher purity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.