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2,2'-o-(2,2'-Diacetamido-2,3,2',3'-Tetradeoxy-6,6'-Di-o-(2-Tetradecylhexadecanoyl)-Alpha,Alpha'-Trehalose-3,3'-Diyl)Bis(n-Lactoyl-Alanyl-Isoglutamine) CAS NO 127896-98-4


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CAS No.:127896-98-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,2'-o-(2,2'-Diacetamido-2,3,2',3'-Tetradeoxy-6,6'-Di-o-(2-Tetradecylhexadecanoyl)-Alpha,Alpha'-Trehalose-3,3'-Diyl)Bis(n-Lactoyl-Alanyl-Isoglutamine) is a sophisticated synthetic glycolipid derivative, representing a high-value building block in advanced pharmaceutical and immunological research. Its complex structure, based on a trehalose core modified with lipid and peptide moieties, is engineered to modulate immune responses and enhance drug delivery systems. This compound is primarily utilized by research institutions and pharmaceutical developers working on novel adjuvants, vaccine formulations, and targeted therapeutic agents.

Application

  • Immunological Adjuvant Development: As a synthetic analog of bacterial cell wall components, it is a key candidate for research into next-generation vaccine adjuvants to enhance immune response.
  • Liposomal and Nanoparticle Drug Delivery: The amphiphilic structure makes it suitable for formulating stable liposomes and nanoparticles for targeted cancer therapies and other advanced drug delivery applications.
  • Toll-like Receptor (TLR) Research: Used in biochemical studies to investigate and modulate signaling pathways involving specific pattern recognition receptors in the immune system.
  • Glycoconjugate Synthesis: Serves as a critical intermediate for the chemical synthesis of complex glycoconjugates for diagnostic and therapeutic purposes.
  • Biomimetic Material Research: Employed in the development of synthetic membranes and biomimetic surfaces that mimic bacterial interactions.

Basic Information

Item Information
Product Name 2,2'-o-(2,2'-Diacetamido-2,3,2',3'-Tetradeoxy-6,6'-Di-o-(2-Tetradecylhexadecanoyl)-Alpha,Alpha'-Trehalose-3,3'-Diyl)Bis(n-Lactoyl-Alanyl-Isoglutamine)
CAS No. 127896-98-4
Molecular Formula C108H196N6O26
Molecular Weight ~2042.78 g/mol
Synonyms Bis(n-Lactoyl-Alanyl-Isoglutamine) Trehalose Derivative; Synthetic Trehalose Glycolipid; Trehalose 6,6'-Dicorynomycolate Analog; TLR Agonist Intermediate; Immunomodulatory Glycolipid; Vaccine Adjuvant Candidate; 2-Tetradecylhexadecanoyl Trehalose Derivative; Lipidated Trehalose Dipeptide
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Quality Control

This high-purity biochemical is manufactured under strict quality control protocols suitable for research and development. Each batch is characterized using advanced analytical techniques to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications such as purity by HPLC, structural confirmation by NMR and MS, and impurity profiles. Our quality system is designed to support cGMP and GLP compliance for critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 2.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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