Description

Trifucosyl-Lewis-B Antigen CAS NO 139568-87-9 is a complex, synthetic carbohydrate antigen, a key oligosaccharide structure in glycobiology research. This compound is critical for studying cell-cell recognition, immune responses, and the molecular basis of blood group determinants. It is an essential reagent for researchers and developers in the fields of glycobiology, immunology, and diagnostic assay development, particularly for investigating host-pathogen interactions and cancer biomarker discovery.

Application

• Glycobiology Research: As a standard or probe for studying fucosylated antigen structures and their biological functions.
• Immunoassay Development: For the design and calibration of diagnostic tests targeting Lewis blood group antigens and related pathologies.
• Vaccine & Therapeutic Research: In the investigation of carbohydrate-based vaccines and anti-adhesion therapies targeting bacterial or cancer cell surface markers.
• Biochemical Tool: For enzyme activity assays (e.g., fucosyltransferases) and as a substrate or inhibitor in enzymatic studies.
• Cell Adhesion Studies: To investigate the role of selectin ligands in inflammation, metastasis, and immune cell trafficking.
• Quality Control Standard: Used as a reference material in the production and validation of glycan arrays and other glyco-analytical platforms.

Basic Information

Product Name	Trifucosyl-Lewis-B Antigen
CAS No.	139568-87-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Lewis b Trisaccharide (Fucα1-2Galβ1-3[Fucα1-4]GlcNAc); Leb Trisaccharide; Blood Group Lewis b Trisaccharide; Fucα1-2Galβ1-3(Fucα1-4)GlcNAc; 2'-Fucosyllactose isomer; H-Type 1/Leb hybrid antigen; Trifucosyl Lewisb
EINECS	Contact for details

Quality Control

Our Trifucosyl-Lewis-B Antigen is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is characterized using advanced analytical techniques including NMR and HPLC. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.