Description

2-Amino-6-(Trifluoromethyl)Benzoic Acid Hydrochloride is a high-purity, functionalized benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an amino group and a trifluoromethyl substituent, makes it a versatile intermediate for creating compounds with tailored biological activity and physicochemical properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a trifluoromethylated aniline moiety to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers and organic electronic materials that benefit from fluorine incorporation.
• Chemical Biology Probes: Utilized to develop fluorescent tags and molecular probes for biochemical and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up manufacturing for clients in life sciences.

Basic Information

Product Name	2-Amino-6-(Trifluoromethyl)Benzoic Acid Hydrochloride
CAS No.	918667-28-4
Molecular Formula	C8H7F3NO2 • HCl
Molecular Weight	241.60 (Free base) / 278.06 (HCl salt)
Synonyms	2-Amino-6-(trifluoromethyl)benzoic acid HCl; 6-(Trifluoromethyl)anthranilic acid hydrochloride; Benzoic acid, 2-amino-6-(trifluoromethyl)-, hydrochloride; 2-Amino-alpha,alpha,α-trifluoro-o-toluic acid hydrochloride; 2-Carboxy-3-(trifluoromethyl)aniline hydrochloride; Anthranilic acid, 6-(trifluoromethyl)-, hydrochloride; 918667-28-4
EINECS	Contact for details

Quality Control

Our 2-Amino-6-(Trifluoromethyl)Benzoic Acid Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.