Description

2-Iodo-6-(Trifluoromethyl)Benzoic Acid is a high-value, multi-functional aromatic building block characterized by its unique combination of iodine and trifluoromethyl substituents. This compound is essential for advanced organic synthesis, offering versatile reactivity for cross-coupling reactions and serving as a key precursor in the development of complex molecules. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the iodine and trifluoromethyl groups.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings to construct complex biaryl systems.
• Ligand and Catalyst Development: Utilized to synthesize novel chelating ligands and organocatalysts for asymmetric synthesis and catalysis research.
• Chemical Biology Probes: Acts as a starting material for creating labeled compounds and molecular probes used in biochemical and diagnostic research.

Basic Information

Product Name	2-Iodo-6-(Trifluoromethyl)Benzoic Acid
CAS No.	914637-39-1
Molecular Formula	C8H4F3IO2
Molecular Weight	316.02 g/mol
Synonyms	2-Iodo-6-(trifluoromethyl)benzoic acid; 6-(Trifluoromethyl)-2-iodobenzoic Acid; Benzoic acid, 2-iodo-6-(trifluoromethyl)-; 2-Iodo-alpha,alpha,α-trifluoro-o-toluic acid; o-Iodo-alpha,alpha,α-trifluorotoluic acid; 2-Carboxy-3-iodobenzotrifluoride
EINECS	Contact for details

Quality Control

Every batch of 2-Iodo-6-(Trifluoromethyl)Benzoic Acid is manufactured and tested under a strict quality management system to ensure consistency and reliability for your critical applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.