Description

4-Fluoro-3-Methylcinnamic Acid is a high-purity fluorinated cinnamic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine and methyl substituents, which are essential for modulating the biological activity, metabolic stability, and physicochemical properties of target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated drug candidates, particularly in oncology, CNS, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and pesticides, where the fluorine atom enhances efficacy and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated aromatic cores in electronic and display materials, improving charge transport and thermal properties.
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes and tags for studying biological processes and protein interactions.
• Polymer Modification: Serves as a monomer or cross-linking agent for introducing fluorinated aromatic groups into specialty polymers.
• Academic & Contract Research: Utilized in methodological studies and as a reference standard in universities and CROs for fluorination chemistry.

Basic Information

Product Name	4-Fluoro-3-Methylcinnamic Acid
CAS No.	913699-82-8
Molecular Formula	C10H9FO2
Molecular Weight	180.18 g/mol
Synonyms	(E)-3-(4-Fluoro-3-methylphenyl)acrylic acid; 3-(4-Fluoro-3-methylphenyl)-2-propenoic acid; 4-Fluoro-3-methyl-trans-cinnamic acid; trans-4-Fluoro-3-methylcinnamic acid; 4-Fluoro-m-methylcinnamic acid; 3-Methyl-4-fluorocinnamic acid; FMMCA; 913699-82-8
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Methylcinnamic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.