Description

3-(Chlorosulfonyl)-5-Fluorobenzoic Acid is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. Its unique structure, featuring both a reactive chlorosulfonyl group and a carboxylic acid moiety, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of sulfonamide-based drugs and fluorine-containing therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom and sulfonyl chloride group enhance biological activity and stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, liquid crystals, and advanced organic materials.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new reaction pathways and creating novel chemical entities.
• Dye and Pigment Intermediate: Employed in the synthesis of complex dyes and functional pigments, leveraging its aromatic core and reactive sites.

Basic Information

Product Name	3-(Chlorosulfonyl)-5-Fluorobenzoic Acid
CAS No.	912577-43-6
Molecular Formula	C7H4ClFO4S
Molecular Weight	238.62 g/mol
Synonyms	5-Fluoro-3-(chlorosulfonyl)benzoic Acid; 3-Chlorosulfonyl-5-fluorobenzoic Acid; Benzoic acid, 3-(chlorosulfonyl)-5-fluoro-; 5-Fluorobenzene-1,3-dicarboxylic acid 1-chlorosulfonyl derivative
EINECS	Contact for details

Quality Control

Every batch of 3-(Chlorosulfonyl)-5-Fluorobenzoic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure compliance with exacting purity and identity specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.