Description

4-Bromo-2-Fluoro-3-Methoxy-Benzoic Acid Methyl Ester is a high-purity, multi-functional aromatic ester building block of significant importance in advanced organic synthesis. Its value lies in the strategic placement of bromine, fluorine, and methoxy substituents, which allow for selective downstream functionalization, making it a versatile intermediate for creating complex molecular architectures. This compound is primarily needed by research institutions and industrial R&D teams in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine and bromine atoms can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its tunable electronic properties.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global fine chemical market.

Basic Information

Product Name	4-Bromo-2-Fluoro-3-Methoxy-Benzoic Acid Methyl Ester
CAS No.	908248-31-7
Molecular Formula	C9H8BrFO3
Molecular Weight	263.06 g/mol
Synonyms	Methyl 4-Bromo-2-Fluoro-3-Methoxybenzoate; Benzoic acid, 4-bromo-2-fluoro-3-methoxy-, methyl ester; 4-Bromo-2-fluoro-3-methoxybenzoic acid methyl ester; 2-Fluoro-3-methoxy-4-bromobenzoic acid methyl ester; Methyl 4-bromo-2-fluoro-3-methoxybenzoate; 908248-31-7; Methyl 2-fluoro-3-methoxy-4-bromobenzoate
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoro-3-Methoxy-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with the standards expected for pharmaceutical intermediates and advanced research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.