Description

4-(4-(Trifluoromethyl)Pyrimidin-2-Yl)Benzoic Acid CAS NO 904310-23-2 is a high-value, multifunctional organic building block featuring a benzoic acid core linked to a trifluoromethyl-substituted pyrimidine ring. This compound is critical for its role in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where the trifluoromethyl group and heterocyclic system impart desirable properties like metabolic stability and enhanced binding affinity. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of small-molecule drugs, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidine moiety.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science: Incorporated into the design of organic electronic materials, such as OLEDs or semiconductors, due to its conjugated structure.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific compounds and advanced intermediates.

Basic Information

Product Name	4-(4-(Trifluoromethyl)Pyrimidin-2-Yl)Benzoic Acid
CAS No.	904310-23-2
Molecular Formula	C12H7F3N2O2
Molecular Weight	268.19 g/mol
Synonyms	2-[4-(Trifluoromethyl)pyrimidin-2-yl]benzoic acid; 4-(4-Trifluoromethyl-pyrimidin-2-yl)-benzoic acid; Benzoic acid, 4-[4-(trifluoromethyl)-2-pyrimidinyl]-; 904310-23-2; 4-(4-(Trifluoromethyl)-2-pyrimidinyl)benzoic Acid; 4-(4-Trifluoromethyl-2-pyrimidyl)benzoic acid
EINECS	Contact for details

Quality Control

Every batch of 4-(4-(Trifluoromethyl)Pyrimidin-2-Yl)Benzoic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are suitable for research and commercial scale applications, with specifications tailored to meet client requirements. A detailed Certificate of Analysis (COA) documenting purity (typically by HPLC), identity (by IR, NMR), and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The product is compatible with strong acid/organic solvent environments but should be kept away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.