Description

Pergolidemesylate CAS NO 99104-23-2 is a mesylate salt form of pergolide, a potent dopamine receptor agonist. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy and consistency of advanced pharmaceutical formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development of treatments for neurological and endocrine disorders.

Application

• Pharmaceutical API: Serves as the key active ingredient in the formulation of prescription medications, particularly for Parkinson's disease and hyperprolactinemia.
• Neurological Research: Used as a reference standard and experimental compound in preclinical and clinical studies targeting dopamine pathways.
• Veterinary Medicine: Employed in the development of treatments for certain hormonal conditions in animals.
• Analytical Standard: Functions as a high-purity certified reference material (CRM) for quality control and method validation in analytical laboratories.
• Process Development: Utilized in process chemistry for the scale-up and optimization of synthetic routes for related pharmaceutical compounds.

Basic Information

Product Name	Pergolidemesylate
CAS No.	99104-23-2
Molecular Formula	C19H26N2S • CH4O3S
Molecular Weight	410.59 g/mol
Synonyms	Pergolide Mesylate; Pergolide Methanesulfonate; 8β-[(Methylthio)methyl]-6-propylergoline Mesylate; LY127809; Permax (brand name variant); Pergolide Methanesulphonate; (8β)-6-Propyl-8-[(methylthio)methyl]ergoline Methanesulfonate
EINECS	Contact for details

Quality Control

Our Pergolidemesylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods, to ensure compliance with ICH guidelines and customer-specific requirements. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.