Description

6H-Purin-6-One, 2,8-Diamino-1,9-Dihydro-9-((2-Hydroxy-1-(Hydroxymethyl)Ethoxy)Methyl)- is a high-purity nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound matters as a critical building block for the synthesis of novel antiviral and anticancer agents, offering researchers a pathway to explore new therapeutic mechanisms. It is primarily needed by R&D laboratories and pharmaceutical manufacturers focused on developing next-generation nucleotide-based drugs, including prodrugs and targeted therapies.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the production of nucleoside analog antiviral medications.
• Antiviral Drug Research: Used in the discovery and development of new therapeutic agents targeting viral polymerases.
• Oncology Research: Investigated as a building block for potential anticancer prodrugs that target specific cellular pathways.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to understand nucleotide metabolism.
• Prodrug Synthesis: Utilized in creating masked or modified nucleosides designed for improved bioavailability and targeted delivery.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Detail
Product Name	6H-Purin-6-One, 2,8-Diamino-1,9-Dihydro-9-((2-Hydroxy-1-(Hydroxymethyl)Ethoxy)Methyl)-
CAS No.	98695-80-8
Molecular Formula	C10H16N6O5
Molecular Weight	300.27 g/mol
Synonyms	9-[(2-Hydroxy-1-(hydroxymethyl)ethoxy)methyl]guanine; H2G; 2,8-Diamino-9-[(2-hydroxy-1-(hydroxymethyl)ethoxy)methyl]-1,9-dihydro-6H-purin-6-one; 2-Amino-9-[(2-hydroxy-1-(hydroxymethyl)ethoxy)methyl]-1,9-dihydro-6H-purin-6-one; 9-(1,3-Dihydroxy-2-propoxymethyl)guanine; GW275175X (former development code); Acyclic guanosine nucleoside analog
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) documenting purity, related substances, and residual solvents are available for every shipment. We support compliance with ICH guidelines and can provide material suitable for use under cGMP conditions for non-clinical studies upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.