Description

H-Orn-Amc CAS NO 98516-75-7 is a specialized fluorogenic peptide substrate widely used in biochemical and pharmaceutical research. This compound is critical for the sensitive detection and quantification of specific enzyme activities, particularly proteases. It is an essential tool for researchers and quality control laboratories in the fields of drug discovery, diagnostic assay development, and life science research.

Application

• Protease Activity Assays: As a fluorogenic substrate for measuring the activity of various proteolytic enzymes, including trypsin, thrombin, and other serine proteases.
• Drug Discovery Screening: Used in high-throughput screening (HTS) platforms to identify and characterize novel protease inhibitors as potential therapeutic agents.
• Diagnostic Development: Employed in the development of sensitive fluorometric diagnostic kits for clinical and research purposes.
• Biochemical Research: A key reagent for studying enzyme kinetics, mechanism of action, and substrate specificity in academic and industrial laboratories.
• Quality Control in Biopharma: Used to monitor and validate the activity and purity of enzyme preparations in biopharmaceutical manufacturing processes.

Basic Information

Product Name	H-Orn-Amc
CAS No.	98516-75-7
Molecular Formula	C₁₆H₂₂N₄O₃
Molecular Weight	318.37 g/mol
Synonyms	H-Ornithine-AMC; Nα-Benzoyl-L-ornithine 7-amido-4-methylcoumarin; Bz-Orn-AMC; Benzoyl-Ornithine-AMC; L-Ornithine, N2-[(7-amino-4-methyl-2-oxo-2H-1-benzopyran-3-yl)carbonyl]-, (S)-; Boc-Orn-AMC (related protected form); Fluorogenic Ornithine Substrate; Protease Substrate 98516-75-7
EINECS	Contact for details

Quality Control

Our H-Orn-Amc is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. The product is light-sensitive and should be handled under appropriate conditions to prevent degradation. For long-term storage, desiccate at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.