Description

2,4,5-Trifluorobenzamide is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials where the introduction of fluorine atoms is critical for modulating biological activity, metabolic stability, and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated drug candidates, including kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of modern herbicides, fungicides, and insecticides where fluorine substitution enhances efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display and lighting materials.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with unique thermal, chemical, or surface properties.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial R&D for exploring new fluorination methodologies and catalytic transformations.
• Fluorinated Dye & Pigment Precursor: Used in the synthesis of specialized colorants with improved lightfastness and solubility.

Basic Information

Product Name	2,4,5-Trifluorobenzamide
CAS No.	98349-23-6
Molecular Formula	C7H4F3NO
Molecular Weight	175.11 g/mol
Synonyms	2,4,5-Trifluorobenzoic acid amide; Benzamide, 2,4,5-trifluoro-; 98349-23-6; 2,4,5-Trifluorobenzene-1-carboxamide; 2,4,5-Trifluorobenzamide (technical grade); 2,4,5-Trifluorobenzamide (98+%); 2,4,5-Trifluorobenzamide (for synthesis)
EINECS	Contact for details

Quality Control

Our 2,4,5-Trifluorobenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications requiring reliable material sourcing for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.