Description

2-(Difluoromethoxy)-4-Chlorobenzoic Acid is a high-purity, multi-functional benzoic acid derivative characterized by its difluoromethoxy and chloro substituents, which confer unique reactivity and stability. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block for synthesizing complex organic molecules. It is essential for R&D and production in the pharmaceutical and agrochemical industries, where precise chemical architecture is required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting metabolic and inflammatory pathways.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging the difluoromethoxy group for enhanced bioactivity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for advanced display technologies.
• Organic Synthesis & R&D: A versatile reagent for introducing the difluoromethoxy moiety into complex molecules in medicinal and materials chemistry research.
• Polymer Additives: Potential use as a monomer or modifier in the production of specialty polymers with specific thermal or chemical resistance properties.

Basic Information

Product Name	2-(Difluoromethoxy)-4-Chlorobenzoic Acid
CAS No.	97914-60-8
Molecular Formula	C8H5ClF2O3
Molecular Weight	222.57 g/mol
Synonyms	4-Chloro-2-(difluoromethoxy)benzoic Acid; Benzoic acid, 4-chloro-2-(difluoromethoxy)-; 2-(Difluoromethoxy)-4-chlorobenzoic acid; 4-Chloro-α,α-difluoro-o-anisic Acid; 97914-60-8; 4-Chloro-2-difluoromethoxybenzoic acid; 2-Difluoromethoxy-4-chlorobenzoic acid
EINECS	Contact for details

Quality Control

Every batch of 2-(Difluoromethoxy)-4-Chlorobenzoic Acid is manufactured under strict quality management systems. Our products undergo rigorous quality testing including HPLC, NMR, and GC-MS to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request, supporting applications in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to minimize exposure to atmospheric humidity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.