Description

2-(Difluoromethoxy)Benzoic Acid is a high-purity, fluorinated aromatic carboxylic acid building block essential for advanced organic synthesis. This compound matters for its unique difluoromethoxy moiety, which is prized for its ability to modulate the physicochemical and metabolic properties of target molecules, enhancing their stability and bioavailability. It is critically needed by pharmaceutical and agrochemical R&D teams for the development of new active ingredients, as well as by manufacturers of specialty chemicals and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluoromethoxy group can improve efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in liquid crystal mixtures for high-performance displays.
• Polymer Modification: Incorporated as a monomer or additive to impart specific properties like chemical resistance or altered surface energy to specialty polymers.
• Organic Electronics: Utilized in the synthesis of charge-transport materials or emissive layers for OLEDs and other electronic devices.
• Chemical Research: A versatile building block for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis in drug discovery.

Basic Information

Product Name	2-(Difluoromethoxy)Benzoic Acid
CAS No.	97914-59-5
Molecular Formula	C8H6F2O3
Molecular Weight	188.13 g/mol
Synonyms	2-(Difluoromethoxy)benzoic acid; Benzoic acid, 2-(difluoromethoxy)-; o-(Difluoromethoxy)benzoic acid; 2-(Difluoromethoxy)benzoic acid, 98+%; 97914-59-5; Difluoromethoxybenzoic acid; 2-Difluoromethoxybenzoic acid; α,α-Difluoro-o-anisic acid
EINECS	Contact for details

Quality Control

Our 2-(Difluoromethoxy)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.