Description

Methyl 4-(Difluoromethoxy)Benzoate is a high-purity organic ester building block characterized by its difluoromethoxy functional group. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, enabling the introduction of fluorine-containing motifs which are critical for modulating the properties of target molecules. It is primarily sought after by research and development teams and production chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic ether structures to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the difluoromethoxy group can improve efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the development of fluorinated compounds for electronic display applications.
• Organic Electronics: Employed in the synthesis of specialized monomers and polymers for materials science research.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and creating novel fluorinated compounds in academic and industrial labs.

Basic Information

Product Name	Methyl 4-(Difluoromethoxy)Benzoate
CAS No.	97914-54-0
Molecular Formula	C9H8F2O3
Molecular Weight	202.16 g/mol
Synonyms	Benzoic acid, 4-(difluoromethoxy)-, methyl ester; Methyl p-(difluoromethoxy)benzoate; 4-(Difluoromethoxy)benzoic acid methyl ester; Methyl 4-(difluoromethoxy)benzoate; p-(Difluoromethoxy)benzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-(Difluoromethoxy)Benzoate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all relevant specifications. We are committed to meeting the stringent requirements of cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, strong bases, and strong oxidizing agents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.