Description

Levodopa 4'-Phosphate CAS NO 97321-87-4 is a phosphorylated derivative of the critical neurotransmitter precursor L-DOPA, offering enhanced stability and bioavailability for advanced pharmaceutical research and development. This compound is essential for scientists exploring novel prodrug strategies and targeted delivery systems for neurological disorders. It serves as a key intermediate and reference standard for manufacturers and R&D laboratories in the pharmaceutical, biotechnology, and fine chemical sectors focused on next-generation treatments for Parkinson's disease and related conditions.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of advanced prodrugs and active pharmaceutical ingredients (APIs) targeting the central nervous system.
• Neurological Research: Used as a reference standard and experimental compound in preclinical studies investigating dopamine metabolism, blood-brain barrier penetration, and treatment mechanisms for Parkinson's disease.
• Prodrug Development: Exploited for creating phosphate ester prodrugs designed to improve the solubility, stability, and targeted delivery of Levodopa.
• Analytical Standard: Employed in analytical laboratories for method development, validation, and quality control (HPLC, LC-MS) of related pharmaceutical products.
• Biochemical Studies: Utilized in enzymatic assays and studies of kinase and phosphatase activity related to dopamine synthesis pathways.
• Fine Chemical Synthesis: Acts as a specialized reagent in custom synthesis and contract manufacturing for high-value, complex molecules.

Basic Information

Product Name	Levodopa 4'-Phosphate
CAS No.	97321-87-4
Molecular Formula	C9H12NO7P
Molecular Weight	277.17 g/mol
Synonyms	L-DOPA 4'-Phosphate; 3-(3,4-Dihydroxyphenyl)-L-alanine 4'-phosphate; (2S)-2-Amino-3-(3,4-dihydroxyphenyl)propanoic acid 4-(dihydrogen phosphate); L-3-(3,4-Dihydroxyphenyl)alanine 4-phosphate; Levodopa phosphate ester; 4'-O-Phosphono-L-dopa
EINECS	Contact for details

Quality Control

Our Levodopa 4'-Phosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and assay, identification by spectroscopic methods (IR, NMR), and control of related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.