Description

(+)-Penflutizide CAS NO 96782-93-3 is a high-purity, single-enantiomer form of the diuretic and antihypertensive agent Penflutizide. This specific stereoisomer is of significant interest in advanced pharmaceutical research and development, particularly for studying structure-activity relationships and metabolic pathways. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, analytical method development, and as a reference standard.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control, method validation, and regulatory submissions in analytical laboratories.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a critical chiral building block in the research-scale synthesis of specialized diuretic and cardiovascular drugs.
• Biochemical Research: Employed in pharmacological studies to investigate the enantioselective interactions, efficacy, and metabolic profiles of thiazide-like compounds.
• Process Development & Optimization: Used by R&D teams to develop and scale up enantioselective synthesis routes for complex molecules.

Basic Information

Product Name	(+)-Penflutizide
CAS No.	96782-93-3
Molecular Formula	C13H19F3N2O4S2
Molecular Weight	388.43 g/mol
Synonyms	(+)-4-(3,4-Dihydro-2-methyl-6-trifluoromethyl-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide); (R)-Penflutizide; Dextro-Penflutizide; (+)-3,4-Dihydro-2-methyl-4-oxo-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; Penflutizide enantiomer; (R)-3,4-Dihydro-2-methyl-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
EINECS	Contact for details

Quality Control

Our (+)-Penflutizide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for research and development purposes. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and enantiomeric excess is supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.