Description

Acetazolamide Sodium is the sodium salt form of acetazolamide, a well-established carbonic anhydrase inhibitor. This compound is a critical active pharmaceutical ingredient (API) and a key intermediate in the synthesis of specialized pharmaceutical formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions developing diuretic and anti-glaucoma medications. The material is supplied as a high-purity powder to meet the stringent requirements of modern drug production.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of prescription medications.
• Diuretic Formulations: Key component in drugs used to treat conditions like edema, congestive heart failure, and certain types of epilepsy.
• Anti-glaucoma Agents: Essential for producing medications that reduce intraocular pressure.
• Metabolic Alkalosis Treatment: Used in therapeutic agents for correcting specific acid-base imbalances.
• Altitude Sickness Prophylaxis: Intermediate in drugs designed to prevent and treat acute mountain sickness.
• Chemical Synthesis: Serves as a crucial intermediate for further chemical derivatization and research into novel carbonic anhydrase inhibitors.
• Biochemical Research: Used in laboratory studies to investigate enzyme inhibition mechanisms and physiological pathways.

Basic Information

Product Name	Acetazolamide Sodium
CAS No.	1424-27-7
Molecular Formula	C4H5N4NaO3S2
Molecular Weight	244.22 g/mol
Synonyms	Acetazolamide Sodium Salt; 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide Sodium Salt; N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide Sodium Salt; Diamox Sodium; Acetazolamide Na; Sodium Acetazolamide; 2-Acetylamino-1,3,4-thiadiazole-5-sulfonamide Sodium Salt
EINECS	Contact for details

Quality Control

Our Acetazolamide Sodium is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide full traceability and detailed Certificates of Analysis (COA) for all shipments, confirming compliance with relevant specifications for identity, purity, and impurities. Our quality commitment supports your regulatory and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.