Description

Hydroflumethiazide CAS NO 135-09-1 is a high-purity diuretic agent belonging to the thiazide class of pharmaceuticals. It is valued for its reliable and specific pharmacological activity in managing fluid retention and hypertension. This compound is essential for pharmaceutical manufacturers and research institutions engaged in the development and production of cardiovascular and diuretic medications.

Application

• Active Pharmaceutical Ingredient (API) in the formulation of prescription diuretic medications.
• Hypertension Treatment as a key component in antihypertensive drug combinations.
• Edema Management for conditions such as congestive heart failure, liver cirrhosis, and renal dysfunction.
• Pharmaceutical Research & Development for studying thiazide pharmacology and developing new therapeutic agents.
• Reference Standard in analytical laboratories for quality control and method validation.
• Preclinical Studies for evaluating efficacy and safety profiles in animal models.

Basic Information

Product Name	Hydroflumethiazide
CAS No.	135-09-1
Molecular Formula	C8H8F3N3O4S2
Molecular Weight	331.29 g/mol
Synonyms	3,4-Dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; Saluron; Diucardin; NSC-107679; Rontyl; Hydra-zide; Flumethiazide derivative; Hydroflumethiazidum
EINECS	205-173-6

Quality Control

Our Hydroflumethiazide is manufactured under strict quality management systems. Each batch is tested to meet high-purity standards suitable for pharmaceutical applications, with specifications aligning with major pharmacopoeial guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity: NMT 0.5% Total impurities: NMT 1.5%
Water (KF)	NMT 1.0%
Residue on Ignition	NMT 0.1%
Heavy Metals	NMT 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.