Description

Benzylhydrochlorothiazide is a thiazide diuretic derivative, recognized for its specific pharmacological activity. This compound is of significant interest in pharmaceutical research and development, particularly for the synthesis of novel therapeutic agents. It is primarily utilized by manufacturers and R&D laboratories in the pharmaceutical and fine chemical sectors. The product is supplied with a focus on high purity and batch-to-batch consistency to meet stringent research and production requirements.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced diuretic and antihypertensive drug candidates.
• Biochemical Research: Used as a reference standard or active compound in studies investigating renal physiology and electrolyte transport mechanisms.
• Analytical Standard: Serves as a high-purity standard for quality control and method development in analytical laboratories (HPLC, LC-MS).
• Fine Chemical Synthesis: Intermediate for the preparation of more complex molecules with tailored biological activities in medicinal chemistry.
• Academic Research: Utilized in university and institutional labs for pharmacological and pharmacokinetic studies.

Basic Information

Product Name	Benzylhydrochlorothiazide
CAS No.	1824-50-6
Molecular Formula	C14H13ClN2O4S2
Molecular Weight	380.85 g/mol
Synonyms	3-(Benzyl)-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; 6-Chloro-3-(phenylmethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; Benzyl Hydrochlorothiazide; 3-Benzyl-6-chloro-7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide; NSC 113986
EINECS	Contact for details

Quality Control

Our Benzylhydrochlorothiazide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with a detailed Certificate of Analysis (COA), which includes results from HPLC, NMR, and other relevant pharmacopeial tests. Specifications are designed to meet the needs of research and cGMP-aligned production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.