Description

Dimethylaminohydroxypropoxytriamterene is a chemically modified derivative of the potassium-sparing diuretic triamterene. This compound is of significant interest in pharmaceutical research and development, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and prodrugs. It serves as a key intermediate for researchers and manufacturers in the fine chemical and pharmaceutical industries seeking to develop new therapeutic agents with optimized pharmacokinetic properties.

Application

• Pharmaceutical Intermediate: Primary use as a building block in the synthesis of advanced diuretic drug candidates and related pharmacologically active molecules.
• Research & Development: Critical for medicinal chemistry programs focused on renal-targeted therapies and structure-activity relationship (SAR) studies.
• Prodrug Synthesis: Utilized in the design and creation of prodrug forms aimed at enhancing bioavailability or targeting specific physiological sites.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory submission support in API manufacturing.
• Chemical Biology Studies: Used as a tool compound in biochemical assays to investigate ion transport mechanisms and related biological pathways.

Basic Information

Product Name	Dimethylaminohydroxypropoxytriamterene
CAS No.	96558-24-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-(2-Dimethylamino-3-hydroxypropoxy)triamterene; 2,4,7-Triamino-6-(2-dimethylamino-3-hydroxypropoxy)phenylpteridine; Triamterene dimethylaminohydroxypropyl ether; DMHP-Triamterene
EINECS	Contact for details

Quality Control

Our Dimethylaminohydroxypropoxytriamterene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.