Description

4-Biphenylhydracrylic Acid, 4'-Fluoro-β-Isopropyl-, (-)- is a high-purity chiral intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a sophisticated building block in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where its specific stereochemistry and fluorinated biphenyl structure are critical. It is needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries focused on creating novel, high-value compounds.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the fluorinated biphenyl moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chiral ligands used in asymmetric catalysis.
• Material Science Precursor: Potential building block for advanced organic electronic materials or liquid crystals due to its rigid, conjugated biphenyl core.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in stereoselective synthesis and fluorination chemistry.

Basic Information

Product Name	4-Biphenylhydracrylic Acid, 4'-Fluoro-β-Isopropyl-, (-)-
CAS No.	95832-07-8
Molecular Formula	C18H19FO3
Molecular Weight	302.34 g/mol
Synonyms	(-)-4'-Fluoro-β-isopropyl-4-biphenylhydracrylic Acid; (2S)-3-[4-(4-Fluorophenyl)phenyl]-2-methylpropanoic Acid; 4'-Fluoro-β-isopropylbiphenyl-4-acetic Acid (enantiomer); [1,1'-Biphenyl]-4-propanoic acid, 4'-fluoro-β-methyl-, (βS)-; 95832-07-8; 4'-Fluoro-β-isopropyl-4-biphenylhydracrylic acid (-)-form
EINECS	Contact for details

Quality Control

Our 4-Biphenylhydracrylic Acid, 4'-Fluoro-β-Isopropyl-, (-)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.